Wound Diagnostics
Auxano Biomedical is developing novel wound diagnostic tools to provide timely insight into the wound environment.
When acute wounds fail to progress beyond the initial inflammatory state, the wound’s chemistry is disrupted and out of balance. Rapid identification of the wound’s dynamics is critical in timely wound care. Bacteria can adhere to damaged tissue and develop into a complex web of biofilm, leading to further chronic infections. In addition, multiple components, such as proteases and growth factors are present in imbalanced ratios leading to ineffective healing.
With rapid wound diagnosis, healthcare providers are empowered to diagnose the wound with accuracy during initial treatment. This rapid determination enables the clinician to appropriately treat the wound and enable faster wound healing.
Auxano’s diagnostic technology is based on an advanced biochemical assay which uses a custom lock-and-key recognition chemistry combined with chromophore release to develop highly specific, stable, and inexpensive binding assays for a wide range of analytes. This unique approach simplifies the assay procedures by avoiding the need for costly antibodies or proteins, secondary labeling or chemical reactions, or complicated instrumentation.
Entirely synthetic molecular pockets are created that selectively bind a target molecule. Embedding this pocket with a weakly-held fluorescent chromophore, enables a displacement reaction to occur in the presence of the target molecule. Using the process of chemiluminescence, the displaced chromophore provides an optical signal that a binding event has occurred.
This technology provides rapid development time, high sensitivity, ease-of-use, and low costs for a range of tests to characterize the wound environment. Small molecules not recognized by traditional lateral flow strips are detected and quantified quickly.
Auxano diagnostics are developed for a number of primary indicating factors in a wound.
Please contact us for more information.
